10 months agoEx-Molde defender Toivo: What Man Utd players can expect from Dempsey

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first_imgAbout the authorPaul VegasShare the loveHave your say Ex-Molde defender Toivo: What Man Utd players can expect from Dempseyby Paul Vegas10 months agoSend to a friendShare the loveFormer Molde defender Joona Toivo is happy for Mark Dempsey over his return to Manchester United.Ole Gunnar Solskjaer’s long-time assistant has followed the Norwegian to Old Trafford and was back helping out at Carrington for the first time this week alongside Mike Phelan, Michael Carrick and Kieran McKenna.”He was really enthusiastic in his coaching. As a person, he has this fire in him – everything is done to the full,” Finland international Toivo told the Manchester Evening News.”I think he is great at creating fighting spirit in the team and encouraging players to be the best they can be. He has a lot of knowledge about football and understands the game really well.”There was a lot of concentration on first touches and observing the play with Mark in training: where and how you took the first touch. He played as a midfielder when he was a player and he often said ‘play what you see’. By that, he also meant to keep it simple and to not try difficult stuff.”He was really like a friend. He’s a guy who loves to tell stories and jokes and loves to make people laugh and play pranks.” last_img read more


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first_imgWolves captain Coady: Past week among best of careerby Paul Vegas12 days agoSend to a friendShare the loveWolves captain Conor Coady says the past week was one of the best of his career.The men in old gold won three matches in nine days going into the international break, including eye-catching victories at Besiktas and Manchester City. Coady told the club’s website: “We won’t forget it. It was an amazing week for this football club, we beat Watford, went to Besiktas and put the effort in with such a small squad, and then went to the home of the champions and put in a brilliant performance.“It was massive for us because a lot of people spoke, saying how we started slow, but we were learning. A lot of players haven’t played in the Europa League before, we’ve had an awful lot of games, and the most important thing was we were listening to the manager after every game and learning. We’ve got a break, which we need, but we’ll move on as soon as possible.” About the authorPaul VegasShare the loveHave your saylast_img read more


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first_imgCrown-Indigenous Relations Minister Carolyn Bennett (APTN file photo.)Kathleen MartensAPTN NewsIt’s nearly official.Crown-Indigenous Relations Minister Carolyn Bennett announced Thursday an “agreement-in-principle” had been reached with former Indian day school students.“Today marks the historic step in that journey towards reconciliation and healing,” Bennett told a news conference flanked by former students.One of those students was Gary McLean of Lake Manitoba First Nation, who filed the class-action lawsuit on behalf of an estimated 200,000 survivors.“We know it’s a new beginning,” McLean told reporters.“For me, without forgiveness, we know things stay the same.”Bennett said the final details still had to be worked out and approved by a court.But she said Canada acknowledged the harms caused by the system that established and guided the schools.“As a result of the harmful and discriminatory government policies at the time, students who attended these schools were subject to sexual, physical and psychological abuse, and forced to abandon their language and culture,” the minister said.Compensation will address individual trauma and future healing, Bennett added.Students in front of Trout Lake Indian Day School in Ontario.Day school students were forced to attend the federally operated schools during the day but could return home at night – a system that began in the 1920s.The suit applies to First Nation, Inuit and Métis students.McLean filed his suit against Canada in 2009.“Thank you for supporting us to get this far,” he said of his legal team, his family and other supporters.Bennett said her government was investing $200 million to support healing, wellness, education language, culture and commemoration “for all those affected by Indian day schools.”kmartens@aptn.ca@katmartelast_img read more


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Major League Baseball8/1021.4 National Basketball Association1636.1% LeaguePlayoff Teams per YearFavorite’s Average Championship Probability Hockey favorites don’t have it too badFor each of the four major North American men’s leagues, playoff field size and average pre-playoff title probability* for favorites, 2006-2018 The Stanley Cup playoffs begin today, with the Presidents’ Trophy-winning Tampa Bay Lighting entering as heavy betting favorites. And for good reason: Their regular season resume is impeccable. They earned 128 points by winning 62 games, placing them in a tie with the 1995-96 Detroit Red Wings for the most regular-season wins in league history.En route to all those wins, the Bolts led the NHL in goals scored, powerplay goals scored, shooting percentage and penalty kill percentage1They finished in basically a three-way tie at the top with the Arizona Coyotes and the Columbus Blue Jackets. and finished third in save percentage. Nikita Kucherov became the first player in more than a decade to register 120 or more points, and Steven Stamkos had the most productive season of his already immensely productive career.Tampa is a balanced juggernaut, and every other team should be very afraid of it.With all that said, it must be noted that regular-season dominance hardly guarantees postseason glory in the NHL. Of the 13 teams that have won the Presidents’ Trophy since the lockout of 2004-05, just two have gone on to lift the Stanley Cup. And of the 10 regular-season winners to earn 120 or more regular-season points in league history, just four have gone on to win professional hockey’s ultimate prize.2Each of those teams played in the 1970s and were called the Montreal Canadiens.Still, NHL favorites3So defined by per-game scoring differential. haven’t had it all that bad since the lockout, especially when compared with the other three major North American men’s leagues. Only NBA favorites have had better championship odds going into the playoffs over the past 13 years. While it might not be as inevitable as, say, the Golden State Warriors winning the NBA title in 2018 (or 2017 or 2015), Tampa’s regular-season dominance suggests that it’s poised to continue this trend. The Bolts scored 103 more goals than they conceded during the regular season; the next best mark was set by the Calgary Flames, who posted a +62 goal differential. The gulf between best and second-best is immense, and it underscores Tampa’s historic regular-season greatness. And indeed, Tampa may be the NHL’s best team since the lockout. National Football League1218.7 National Hockey League1623.5 Hockey-Reference.com’s Simple Rating System (SRS), which estimates the strength of every team in the NHL,4Technically speaking, SRS measures a team’s average goal differential after adjusting for strength of schedule. reiterates just how special this Bolts group is. From 2005-06 to 2017-18, just three teams finished the regular season with an SRS better than 1, and no team eclipsed 1.2. The most recent team to do so — the 2012-13 Chicago Blackhawks — won the Stanley Cup. Tampa finished the 2018-19 regular season with an SRS of 1.21. All signs are pointing to late-spring celebrations on the Gulf Coast.Tampa’s only real concern at the moment is the health of Victor Hedman, the reigning Norris Trophy winner for the top defenseman. The Swede missed Tampa’s final three games with an “upper-body injury.” Hedman has a history of concussions, and “upper-body injury” is often NHL front-office code for concussion. The slick-skating defenseman is Tampa’s fourth-highest scorer, its power-play quarterback and the leader of a rearguard partially responsible for that gaudy goal differential. The Bolts can probably survive a first-round tilt against a slightly better-than-average Blue Jackets team without Hedman, but things might not be as easy against subsequent teams.If there’s a cautionary tale for this iteration of the Bolts, it’s that Red Wings team from 1995-96: Detroit earned the second-most regular-season points in NHL history and boasted two of the league’s best offensive players (Sergei Fedorov and Steve Yzerman) and the league’s reigning Norris Trophy winner (Paul Coffey) and yet failed to advance beyond the Western Conference finals. In the NHL, history is written between April and June, not October and April. Tampa is on top of the hockey world at the moment. But that world could change significantly in a matter of weeks. * Based on a logit regression between per-game scoring differential and championships won for each league.Source: Sports-Reference.com read more


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OSU players return to the field after halftime in the Orange Bowl against Clemson at Sun Life Stadium Jan. 3. OSU lost 40-35. Credit: Shelby Lum / Photo editorMIAMI GARDENS, Fla. — This wasn’t how it was supposed to end.As Clemson redshirt-senior quarterback Tajh Boyd took a knee to run out the clock in the 2014 Discover Orange Bowl — signaling his team’s 40-35 victory over the Ohio State Buckeyes (12-2, 8-1) — a harsh reality was setting in for OSU seniors.Despite winning 24 straight games under coach Urban Meyer, the 2013 senior class has no postseason victories to their name, unless they were redshirted during their Buckeye career and were thus a part of the team of 2010 Rose Bowl champions.Between a loss in the Orange Bowl this season, a bowl ban in 2012-13 season, falling short in the 2012 Gator Bowl and getting the 2011 Sugar Bowl win vacated, something will always be missing from a group that had championship expectations.“It’s always going to be hard. My college career did not end the way I thought it would or I wanted it to,” redshirt-senior left tackle Jack Mewhort said following the loss to the Tigers (11-2, 7-1).Regardless of the team’s postseason shortcomings in recent years, that’s not how Mewhort and company want to be remembered.“I think we’re very resilient. I think we’re hard workers, good people. Good football players, even better people,” Mewhort said. “I’d like to take that to be the legacy. Obviously we dropped a few tough ones here at the end. We would have liked to go out on top, but I think we set a standard for these younger guys.”From the depths of a 6-7 season in 2011 capped with the Gator Bowl loss to Florida, this year’s class of seniors will be remembered fondly by its head coach even though the group fell short in this season’s biggest games.“Senior class, we just said an emotional goodbye to them,” Meyer said after the Orange Bowl loss. “It’s not because they’re seniors, it’s because of what they’ve done. I tried to make that perfectly clear. Just because you stay some place for a couple years doesn’t mean you deserve that respect. It’s what you did, and how you did it.”The seniors on the offensive side of the ball turned in a record-setting season in their last year at OSU, setting school records for points (637), points per game (45.5), yards per game (512.0), passing touchdowns (38), first downs (361) and rushing yards (4,321).The Buckeyes had chances to win both postseason games late, but ultimately fell short. It is that unwillingness to give up that sets them apart, senior wide receiver Corey “Philly” Brown said after the loss to the Tigers.“(We have) great leadership, especially the senior class. It’s a tough football team. A team that will never give up,” Brown said.When Meyer’s reign began in 2012, a change in the culture came along with it, something Mewhort said was not an easy adjustment.“I know it looks like immediately the next season after going 6-7 we came back and go 12-0, but it was not immediate — at all,” Mewhort said. “It started at 5 a.m. in January of last year. Every day we came to work and we grinded hard.”Aside for Ryan Shazier — who declared for the NFL Draft Saturday — OSU will be leaning on juniors like quarterback Braxton Miller, tight end Jeff Heuerman, defensive lineman Michael Bennett and wide receivers Devin Smith and Evan Spencer in 2014 to follow in the footsteps of a class who Meyer thinks has a bright future.“It will be great. A student-athlete at Ohio State University, (will) get a great degree, and go on and build for the future,” Meyer said. “It’s going to sting for a while, probably a long while, because we just didn’t finish, and it was right there to finish.“This year’s senior class … When I looked around the room, every one of them could impact that play. And that’s the sign of a decent senior class.”No matter how it ended, Mewhort said being remembered for getting the program “back to where Ohio State should be” is the most important thing.“Talking about the last two games, obviously we would have liked to come out on top of those but I think our seniors did a good job of setting the template of how to come to work every day,” Mewhort said. “Do things the right way on and off the field. Hopefully we’ll be remembered for that.” read more


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Ohio State senior forward Sammy Edwards surveys the field during the second half of the Buckeyes’ 7-0 win against Illinois at Jesse Owens Memorial Stadium on Sept. 14. Credit: Colin Hass-Hill | Sports EditorThe No. 15 Ohio State women’s soccer team (11-2-1, 6-1-0 Big Ten) extended its unbeaten streak to five games with a 1-0 win over Michigan (5-4-6, 2-3-3 Big Ten) Sunday at Jesse Owens Memorial Stadium. Senior forward Sammy Edwards led the way for the Buckeyes with five shots and a goal. The Buckeyes had their breakthrough in the 81st minute as senior forward Eleanor Gabriel tore down the right side of the field and crossed the ball in through the penalty area to a streaking Edwards, where the ball was one timed into the back of the net, the lone goal of the game.The rivalry with Michigan delivered another intense game, as physical play dominated the matchup and it was clear neither team would allow any easy goals. “Just knowing it’s Michigan I think everyone is a little more hype,” Edwards said. “I definitely come into this game very pumped up and I know it’s across the board.”Ohio State outshot Michigan 17-4, and Kerr needed to make only one save. The shutout marks Ohio State’s fifth consecutive clean sheet, the longest streak since 2012. The first half provided a slow, tactical pace from both teams, neither giving the other strong chances at the goal. Most of the half was played around the midfield area as both teams battled back and forth with strong defensive plays. “It’s definitely a mental battle,” Edwards said. “A win on a Sunday can be hard. We sometimes come out slow just from having dead legs but instead of coming out slow we came out fast and set the tone for the game.”Possession favored the Buckeyes in the first half, but both teams spent most of the half measuring the defensive style of the other. Ohio State outshot the Wolverines 6-1, despite neither team finding any strong offensive footing. Michigan’s only shot in the first half came close to finding the back of the net as midfielder Sara Stratigakis sliced into the penalty area and fired a strong shot on goal, which was saved by Ohio State goalkeeper Devon Kerr. The best chance of the half for the Buckeyes came in the 33rd minute on a corner from midfielder Nikki Walts. The ball slipped out of the pack of players to Edwards, who connected with a shot that sailed just above the crossbar. The second half began with a much more frantic pace, with Ohio State leading several quick offensive attacks, which resulted in three shots.Michigan’s best opportunity of the half came on a loose ball play in the 61st minute as a defensive error led to an open lane for midfielder Katie Foug, whose close-range shot flew just over the goal. The Buckeyes had a prime chance to score in the 74th minute as a grounded cross rolled through the box to Edwards, whose shot hit the left post. Michigan goalkeeper Sarah Jackson dove for the ball and missed as it rebounded off the post right on the goal line, but all Ohio State players could do was watch as the ball was cleared by a Michigan defender. “We rely on each other,” Edwards said. “You turn to your teammates and realize that you’re not the only tired one, and you’re not alone when you hit the post. We just look to each other when someone messes up, and I think that contributes to our success a lot.”Ohio State maintained an aggressive play style for the rest of the game, not letting Michigan create many attacks and pelting the Michigan keeper with more shots. Michigan continued trying to apply pressure and equalize, but the patient attack and rigid defense of Ohio State proved too much for the Wolverines. Ohio State’s next game is Thursday against Big Ten opponent Maryland. read more


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first_imgSpanish cable operator ONO has named Patricia Ferruz as director of its residential business.Ferruz previously worked for consulting firm McKinsey & Company, specialising in telecom companies. She holds a degree in industrial engineering from the Universidad Politécnica de Cataluña and an MBA from MIT.last_img



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first_img This story originally appeared on Reuters Learn how to successfully navigate family business dynamics and build businesses that excel. Image credit: Pixabay March 16, 2016 Add to Queue Free Webinar | July 31: Secrets to Running a Successful Family Business Apple: Founding Fathers Would Be ‘Appalled’ by Government’s iPhone Request Reuters center_img –shares Legal The U.S. founding fathers “would be appalled” by a Department of Justice request to unlock an encrypted iPhone, Apple Inc. said on Tuesday in its final brief before a court showdown next week.Apple is fighting a court order obtained by the Federal Bureau of Investigation last month, which requires the company to write new software to disable passcode protection and allow access to the phone used by one of the San Bernardino, Calif. shooters, Rizwan Farook.Apple on Tuesday said Congress had declined to give the Justice Department the authority to compel Apple’s help.”Although silence is sometimes a weak indicator of intent, it is a different story when Congress actively considers legislation to address a major policy issue, yet deliberately declines to enact it,” Apple said.According to Apple, the government also believes the courts can order private parties “to do virtually anything the Justice Department and FBI can dream up. The Founders would be appalled.”In a statement, the Justice Department said it looked forward to responding to Apple’s arguments in court.”As we have said in our filings, the Constitution and the three branches of the federal government should be entrusted to strike the balance between each citizen’s right to privacy and all citizens’ right to safety and justice,” spokeswoman Emily Pierce said. “The Constitution and the laws of the United States do not vest that power in a single corporation.”Apple and the government have had several heated exchanges in court papers over the case in which law enforcement officials have said last December’s shootings by Farook and his wife, Tashfeen Malik, were inspired by Islamist militants. The FBI wants to read data on the phone to try and find out whether or not the couple had contacts with militant groups.The government has claimed Apple is refusing access as part of a “marketing strategy” to show off its commitment to customer privacy. In response, Apple senior director Robert Ferrini filed a sworn statement saying Apple has created nearly 1,800 advertisements worldwide since rolling out its iOS 8 operating system in October 2014, generating an estimated 253 billion impressions worldwide.”Of those advertisements, not a single one has ever advertised or promoted the ability of Apple’s software to block law enforcement requests for access to the contents of Apple devices,” Ferrini said.Repeating some of the arguments from its previous court filings, Apple on Tuesday said the court order violated free speech rights by compelling it to create software, and contradicted the purpose of a 1994 law called CALEA, which regulates government surveillance of communications networks.The government has asked Apple to create a new version of its operating system, which would circumvent a feature that erases data on an iPhone after too many incorrect passwords are entered.In a court filing last week the government suggested that it could also have the authority to seek Apple’s source code and signing key. If the government did obtain that code, experts said it could access an unlimited number of devices, not just Farook’s phone.In response to the government, Apple said “the catastrophic security implications of that threat only highlight the government’s fundamental misunderstanding or reckless disregard of the technology at issue and the security risks implicated by its suggestion.”Additionally, Apple senior vice president of software engineering Craig Federighi said the company has never provided any government with its proprietary source code, according to a sworn statement filed in court.Farook and Malik shot and killed 14 people on Dec. 2 at a holiday party. The couple later died in a shootout with police.Tech industry leaders including Google, Facebook and Microsoft and more than two dozen other companies filed legal briefs earlier this month supporting Apple. The Justice Department received support from law enforcement groups and six relatives of San Bernardino victims.(Reporting by Dan Levine in San Francisco and Dustin Volz in Washington; Additional reporting by Joseph Menn in San Francisco; editing by Grant McCool) Next Article 4 min read Register Now »last_img read more


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first_img This story originally appeared on Reuters September 16, 2016 Autoplay: On | Off Figure Out Your Family Tree Just in Time For Father’s Day Congress Is Back as President Trump Heads to the UK Heat Snapshot 2020 Ballots May Have a New Box to Check ? Vice President Turning Up the Heat in the Southeast for Holiday Weekend Up Next: 2 Musts for Tackling Allergy Season Enroll Now for $5 2 Delicious Summer Entertaining Ideas Cannes: ticketless festival-goers seek seats for films Summer Beauty Survival Must-Haves 3-D Printing BACK Delicious Summer Entertaining Ideas Summer is here and there are some great looks this season for women of all shapes and sizes. Check out the hottest styles for hourglass, rectangle and pear shaped women. Cannes: ticketless festival-goers seek seats for films Airbnb Wants to Take You on an All-Inclusive Adventure Figure Out Your Family Tree Just in Time For Father’s Day Add to Queue Albany Steps Closer to Releasing Trump’s State Tax Returns After Assembly Vote A Safe Way to Get Rid Of Bugs in Your Home 2020 Toyota Camry Learn from renowned serial entrepreneur David Meltzer how to find your frequency in order to stand out from your competitors and build a brand that is authentic, lasting and impactful. 2 min read Southern Charm’ Star Talks New Season HBO’s ‘Chernobyl’ Phenomenon US Navy: Russian destroyer almost collided with cruiser in the Philippine Sea Economy adds 75K jobs in May Silicon Valley 3-D Printing Startup Gets $81 Million in New Funding Memorial Day Weekend Heat Wave Could Smash May Records Photo of solider placing flag at Tomb of Unknown Solider goes viral Justin Bieber Launches Plant-Based Deodorant Summer Beauty Survival Must-Haves Rock and Roll Hall of Fame Guitarist Don ‘Fingers’ Felder Releases New Album A Petition Is Coming ? for a ‘Game of Thrones’ Final Season Do-Over North Carolina superintendent says new app can help reduce violence in schools Figure Out Your Family Tree Just in Time For Father’s Day Father’s Day is such a special moment for the whole family to come together and spend quality time with one another – and those are moments dad will cherish. What better way for dad to connect with his loved ones than learning about his family’s stor Lifeminute tv Fireside Chat | July 25: Three Surprising Ways to Build Your Brand The requested video is no longer available DiCaprio, Pitt want to team up again after Tarantino hit 2 Musts for Tackling Allergy Season IHOP Sees Explosive Growth in To-Go Sales Swimwear Styles for All Shapes and Sizes Former world paragliding champion Rémy soars over Pyrenees Embed A LifeMinute with Ryan Seacrest A LifeMinute with John Lithgow: The Actor Discusses His Latest Projects Beyond Meat Earnings Are Beyond Analyst Expectations –shares Memorial Day Weekend Heat Wave Could Smash May Records Next Article Figure Out Your Family Tree Just in Time For Father’s Day Airbnb Wants to Take You on an All-Inclusive Adventure Economy adds 75K jobs in May Sophie Turner Talks Dark Phoenix, Co-Star Jessica Chastain and GoT Sophie Turner Talks Dark Phoenix, Co-Star Jessica Chastain and GoT How Human Behavior is Hurting Animals and What We Can Do to Protect Them Carbon, a Silicon Valley startup that is developing 3-D printers to produce medical devices and car parts on demand, said on Thursday it had closed on $81 million in funding that brought the total it has raised to $222 million.”We wanted to go find investors that share the scope of our vision and realize what we are talking about here is industrial re-invention,” Kirk Phelps, Carbon vice president of product management, told Reuters at the company’s headquarters in Redwood City, Calif.Founded in 2013, Carbon said the funding round was led by automaker BMW Group, industrial conglomerate General Electric Co., optics and imaging products company Nikon Corp. and chemical manufacturer JSR Corp. They joined earlier investors Google Ventures and top tech venture capital firm Sequoia.”They did an incredibly good job in getting investors,” said Terry Wohler of Wohler Associates, an additive manufacturing consultancy firm based in Colorado.However, Wohler said “the jury is still out” on whether Carbon’s technology can match the durability of injection molding, the current industry standard for producing plastic products, or come close to its price point.The company’s first commercial 3-D printer, the M1, is available for a $40,000 annual subscription. It uses software that controls a photochemical process that balances the way ultraviolet light and oxygen react within a pool of polymer resin to print plastic objects.Carbon has developed various resins to diversify what can be printed. It uses heat-resistant hard resins for exterior automotive parts and soft elastic biodegradable resins for medical devices like heart stents.The company says it can print up to 100 times faster than rival 3-D printing companies. That would be a selling point to the manufacturing industry, which until now used 3-D printing primarily as a prototyping tool.”You can imagine that if we give clients a great on-demand manufacturing tool, it’s not just the product that changes,” Phelps said. “It’s the business that changes.”Carbon said it would use the proceeds and newly formed partnerships with JSR and Nikon to fund its first push into international markets and to develop its technology further.(Reporting by Ben Gruber in Redwood City, Calif.; Editing by Lisa Von Ahn) New York takes aim at skyscrapers’ sky-high energy usage Figure Out Your Family Tree Just in Time For Father’s Day A Safe Way to Get Rid Of Bugs in Your Home Privacy Policy   |   Terms of Use IndyCar Beefing Up Business as Indy 500 Approaches The company’s first commercial 3-D printer, the M1, is available for a $40,000 annual subscription. A Petition Is Coming ? for a ‘Game of Thrones’ Final Season Do-Over Reuters Saint Laurent dazzles with men’s collection on Malibu beach Sunlight Shines on Grand Canyonlast_img read more


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Reviewed by James Ives, M.Psych. (Editor)Dec 14 2018A population heath study from the Regenstrief Institute and Indiana University Center for Aging Research has determined that haloperidol, the drug most commonly used to treat delirium in hospital medical and surgical intensive care units (ICUs), did not benefit elective thoracic surgery ICU patients when given prophylactically, with the possible exception of those who have had surgery to remove their esophagus. The study results indicate the need for a personalized approach to delirium in the ICU.The work is the first to evaluate the use of the antipsychotic drug haloperidol to reduce post-operative delirium in elderly patients undergoing elective non-cardiac thoracic surgery.Researchers found no differences in delirium incidence or severity between haloperidol and placebo in patients who had undergone elective non-cardiac thoracic surgery except in the small number of study participants who were admitted to the ICU after removal of the esophagus, a procedure known as esophagectomy. Removal of this organ is a treatment for esophageal cancer.”Our work suggests that just as you can’t lump all cancer patients together for treatment, you can’t put all delirium patients in the same bucket,” said Regenstrief Institute investigator Babar A. Khan, M.D., M.S., who led the new study published in the Journal of the American Geriatrics Society. “We need a personalized approach to delirium, focusing on people at higher risk of developing this complication.”He notes that while elective surgery patients typically are healthier than other ICU patients, they are very much at risk of delirium. He counsels those considering elective surgery to consult with their primary care clinicians and their surgeon to weigh the significant risks of delirium with the benefits of the proposed procedure.Related StoriesBacteria in the birth canal linked to lower risk of ovarian cancerNew study to ease plight of patients with advanced cancerCancer killing capability of lesser-known immune cells identifiedDr. Khan is also a co-author of the groundbreaking October 2018 New England Journal of Medicine study that reported that haloperidol did not significantly alter the duration of delirium in ICU patients.”Because we now know that haloperidol, the most commonly used drug to treat ICU delirium doesn’t, with possibly few exceptions, work, we need to focus on nonpharmacological therapies and vigilantly curtail administration of drugs that are harmful to the brain, especially the aging brain,” said Dr. Khan.Approximately five million Americans are admitted to a surgical or medical ICU annually. Delirium, a sudden and serious change in brain function causing confusion, occurs in as many as three quarters of those treated in the ICU. Causes include sepsis, metabolic problems such as liver and kidney disease as well as drugs that injure the brain.Individuals who experience delirium are more likely to have longer hospital stays and hospital-associated complications. They also have a greater likelihood of dying in the hospital for up to a year after their hospital stay than ICU patients who did not experience delirium. They are also more likely to lose physical functioning and experience cognitive impairment.”This landmark study represents a first attempt to reduce the incidence and morbidity of delirium in the postoperative patient,” said thoracic surgeon Kenneth Kesler, M.D., Harris B. Shumacker Professor of Surgery at IU School of Medicine, senior author of the JAGS study. “Although unfortunately an overall negative study, it does move us forward by identifying both a subset of patients who may benefit from haloperidol prophylaxis and those patients who are at risk for delirium following large surgical procedures.” Source:https://www.regenstrief.org/article/icu-acquired-delirium-requires-personalized-approach/ read more