Mourinho’s time runs out at Chelsea

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first_img “The club wishes to make clear Jose leaves us on good terms and will always remain a much-loved, respected and significant figure at Chelsea. His legacy at Stamford Bridge and in England has long been guaranteed and he will always be warmly welcomed back to Stamford Bridge.” Throughout weeks of turmoil, Mourinho retained the support of fans who loyally chanted his name. There was no immediate announcement about a replacement ahead of tomorrow’s home match against Sunderland. “The club’s focus is now on ensuring our talented squad reaches its potential,” Chelsea said. First hired by Chelsea in 2004, the Portuguese coach ended a 50-year league-title drought and defended the trophy among other successes before losing a power struggle three years later with Abramovich. He was brought back in 2013 by Abramovich in an attempt to restore unity to the club following the divisiveness caused by the appointment of Rafa Benitez as interim manager, who was regularly jeered by fans. Mourinho presented himself as a figure transformed from the fiery character who fell out with Abramovich in 2007, but it was not long before the combativeness returned. He survived a first trophyless season back at Stamford Bridge before cruising to the title in May. “All at Chelsea thank Jose for his immense contribution since he returned as manager in the summer of 2013,” Chelsea said. “His three league titles, FA Cup, Community Shield and three League Cup wins over two spells make him the most successful manager in our 110-year history.” STILL ON GOOD TERMS LONDON (AP): Jose Mourinho’s second spell at Chelsea ended prematurely Thursday with the team in decline only seven months after the Portuguese coach won his third Premier League title with the club. Although Chelsea are only one point above the relegation zone, the 52-year-old Mourinho had been defiantly insisting he was the right man to oversee the team even as it collapsed on the field with a succession of humiliations. Mourinho’s departure, characterised by Chelsea as “mutual”, came two and a half years after his return to Stamford Bridge and only four months into a new four-year contract. The worst-ever start for a defending champion team in the Premier League was compounded on Monday by a 2-1 loss at surprise leaders Leicester. After the match, Mourinho said he was “betrayed” by his players. The personal conduct of the self-styled ‘Special One’ was also proving damaging to Chelsea, with Mourinho engaging in public spats with referees, a television-rights holder and even the club’s doctor over the last year. Chelsea are engaged in an ongoing legal battle with Dr Eva Carneiro after she was publicly criticised and then demoted following Mourinho’s opening-day outburst. Now it is Mourinho leaving Chelsea, with Russian billionaire owner Roman Abramovich preparing for his 10th managerial appointment since buying the team in 2003 and transforming its fortunes with a huge injection of cash. “Both Jose and the board agreed results have not been good enough this season and believe it is in the best interests of both parties to go our separate ways,” Chelsea said in a statement.last_img read more


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first_imgWatching molecular machines at work in living cells should be as fascinating as watching a city through a magnifying glass.Observing biological nanotransporters (Science Daily). What if you could watch drawbridges working on the head of a pin? Something like that, but far smaller, works inside your cells. There’s a “nanoporter” that uses ATP to transport cargo in and out of cell membranes. This system is not as simple as A-B-C, even though it has that name.“ABC transporters are fascinating biological nanomachines,” says Lars Schäfer, head of the Molecular Simulation research group [at Ruhr-University Bochum]. These proteins couple the binding and chemical cleavage of ATP molecules, the chemical energy unit of the cell, with the transport of molecules through biological membranes….“Our results show how the binding of ATP molecules induces structural changes in the transporter that are ultimately required to carry substrate molecules through the membrane,” explains Hendrik Göddeke, co-author and doctoral researcher in Lars Schäfer’s group.Study reveals the inner workings of a molecular motor that packs and unpacks DNA (Phys.org). A chromosome remodeler named INO80 is performing onstage at the Ludwig Maximilian University of Munich: on the microscope stage, that is. Researchers at LMU watched the act of “astonishing precision” as it worked on its “heavy-duty reorganizational task” of wrapping DNA around chromatin.Chromatin remodelers have an essential role as they are molecular machines: they unpick and unpack segments of the DNA by sliding nucleosome spools back and forth, replacing individual histones, freeing up the DNA for transcription, and finally compacting it again, when the job is done. Since all of this happens in a highly dynamic fashion, chromatin remodelers enable cells to react rapidly to alterations in their environment – and this holds for brewer’s yeast as well as for human cells.The clouds of spaghetti that keep DNA data safe (Science Daily). Computer systems worry about data breaches, and so do cells. The cell nucleus is like a massive library read by numerous machines. They deliver information to the cytoplasm outside the nucleus, but only certain molecules can get in or out. This article describes some of the data protection systems provided by the Nuclear Pore Complexes (NPCs), some of the most complex machine systems in cells.Molecular machines (Illustra Media)Cells can avoid “data breaches” when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert Einstein College of Medicine have shown. Their study appears in the March 23 issue of the Journal of Biological Chemistry….To travel through NPCs, many molecules must be attached to proteins called transport factors (TFs), which act as shuttles that the NPC recognizes. But the NPC faces a challenge: It must accurately recognize and bind to TFs to let them through without admitting unwanted traffic, but it must let them through quickly — in a matter of milliseconds — in order for the cell to be able to do its duties. Proteins known to accurately bind to specific molecules, like antibodies, normally stay stuck to their targets for periods of up to months.“How on Earth do you have the kind of specificity that we see in protein-protein interactions like antibodies, and yet have the kind of speed that we see with water off a Teflon pan?” asked Michael Rout, professor at Rockefeller University who was one of the co-lead authors of the work.The spaghetti trick involves many intrinsically-disordered proteins in the NPC, looking somewhat like strands of spaghetti, making “many quick, transient contacts between transport factors” and nuclear proteins. How can we visualize this? “I can’t think of any analogy in normal life that does what this does,” Rout said. “You’ve got this blur of (amino acids) coming on and off (the transport factor) with extraordinary speed.” Maybe security engineers could learn something from this technique.Scientists map the portal to the cell’s nucleus (Science Daily). In this second article from Rockefeller University about the NPC, Rout did find one analogy:It reminds us of a suspension bridge, in which a combination of sturdy and flexible parts produce a stress-resilient structure, says Michael P. Rout, who led the work together with Brian T. Chait.The pore complex contains 552 component proteins, called nucleoporins, and scientists hadn’t previously known how they all fit together. It took a combination of approaches to assemble a comprehensive map of these pieces.Sadly, after comparing the NPC to lesser systems designed intelligently by humans, Rout ascribes it all to evolutionary chance. “Evolution has enclosed it with a double membrane, the nuclear envelope,” the article says, going on to visualize some unobserved miracles:The pore complex first emerged when single-celled organisms — the only living things at the time — acquired special compartments containing organ-like structures, including the nucleus, which houses the cell’s genetic code.Strings of electron-carrying proteins may hold the secret to ‘electric bacteria’ (Phys.org). This article suggests that some bacteria may have the ability to transfer electrons from the inside to the outside environment, using “micro machines” that turn on the power to extract energy from the environment. “Could a unique bacterium be nature’s microscopic power plant?” asks Moh El-Naggar, scientist at USC. Isn’t it nice to know that bacteria, “wired for survival” as among the smallest organisms on earth, are “highly evolved machines”?Microbiologists, can you please please turn off the obligatory Darwinspeak and just tell us the facts of what you are looking at? You’re beginning to sound like comedians. (Visited 422 times, 1 visits today)FacebookTwitterPinterestSave分享0last_img read more


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first_imgWhy Tech Companies Need Simpler Terms of Servic… Top Reasons to Go With Managed WordPress Hosting Tags:#Product Reviews#web frederic lardinois Related Posts center_img A Web Developer’s New Best Friend is the AI Wai… If you ever wanted to quickly share or collaborate on a simple sketch online, here is a fun new tool to try. With FlockDraw, you can draw simple sketches collaboratively in your browser in real-time. Up to 50 people can draw simultaneously on a single whiteboard. FlockDraw doesn’t limit the number of people who can watch. FlockDraw feels a bit like a pre-Windows7 version of MS Paint, and isn’t anywhere close to being a replacement for a full-blown design app like Balsamiq, or a browser-based image editing suite like Aviary. The service, however, makes it very easy and fun to create simple drawings and sketches in real-time.Not a lot of Features – But That’s the PointFlockDraw offers a simple set of basic tools: freehand drawing, lines, eraser and text. You can also change the color and size of your font or pencil. There are no fancy tools here, but what is there is more than enough to draw a quick sketch. It’s important to note that these FlockDraw rooms are meant to be disposable — once the last person leaves the room, the image disappears. Two features — embedding the whiteboard and saving files — are currently disabled, though Blake tells us that they will soon return. Users will be able to save files as JPEGs, and embed the whiteboard on their social networking sites or blogs.Overall, the service, which was founded by Dan Blake (of TinyChat fame) and Ryan Hileman, is extremely easy to use. Just head to the front page and click “Start Drawing.” You can also start a new FlockDraw room by simply appending more than 3 characters to the FlockDraw URL (http://flockdraw.com/rwwwhiteboard, for example). 8 Best WordPress Hosting Solutions on the Marketlast_img read more


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first_imgMan Utd would consider buyout clause for Pogba’s new contractby Paul Vegasa month agoSend to a friendShare the loveManchester United would consider including a buyout clause in Paul Pogba’s new contract.The Times says talks between the two parties commenced on Tuesday morning.However, it’s suggested any agreement would be based on an acceptance Pogba will eventually leave.Tied to United until 2021, the aim for the club would be to maintain his transfer value.And as a gesture of goodwill, United would be willing to include a buyout clause in the new deal so preventing them from blocking a departure. TagsTransfersAbout the authorPaul VegasShare the loveHave your saylast_img


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first_imgAbout the authorCarlos VolcanoShare the loveHave your say Spain U21 coach De la Fuente happy with attitude of Barcelona whiz Ansu Fatiby Carlos Volcano10 days agoSend to a friendShare the loveBarcelona attacker Ansu Fati could debut with Spain’s Under-21 side against Montenegro on Tuesday.But his national team coach Luis de la Fuente doesn’t want to single the player out.The Barcelona forward replaced Carles Perez in the La Rojita squad, after the latter withdrew due to injury.”[Ansu Fati] was very calm when he arrived and wants to enjoy his football like the others,” De la Fuente told MARCA. “There are players who make a difference immediately, he is not the only case, but he has various qualities for his age and youth.”He has many chances to improve but we have to be cautious.”He is just starting out and we have to help him.”Ansu’s situation is the same as [Iker] Muniain’s in his day.”We have to treat him normally.” last_img read more


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OSU players return to the field after halftime in the Orange Bowl against Clemson at Sun Life Stadium Jan. 3. OSU lost 40-35. Credit: Shelby Lum / Photo editorMIAMI GARDENS, Fla. — This wasn’t how it was supposed to end.As Clemson redshirt-senior quarterback Tajh Boyd took a knee to run out the clock in the 2014 Discover Orange Bowl — signaling his team’s 40-35 victory over the Ohio State Buckeyes (12-2, 8-1) — a harsh reality was setting in for OSU seniors.Despite winning 24 straight games under coach Urban Meyer, the 2013 senior class has no postseason victories to their name, unless they were redshirted during their Buckeye career and were thus a part of the team of 2010 Rose Bowl champions.Between a loss in the Orange Bowl this season, a bowl ban in 2012-13 season, falling short in the 2012 Gator Bowl and getting the 2011 Sugar Bowl win vacated, something will always be missing from a group that had championship expectations.“It’s always going to be hard. My college career did not end the way I thought it would or I wanted it to,” redshirt-senior left tackle Jack Mewhort said following the loss to the Tigers (11-2, 7-1).Regardless of the team’s postseason shortcomings in recent years, that’s not how Mewhort and company want to be remembered.“I think we’re very resilient. I think we’re hard workers, good people. Good football players, even better people,” Mewhort said. “I’d like to take that to be the legacy. Obviously we dropped a few tough ones here at the end. We would have liked to go out on top, but I think we set a standard for these younger guys.”From the depths of a 6-7 season in 2011 capped with the Gator Bowl loss to Florida, this year’s class of seniors will be remembered fondly by its head coach even though the group fell short in this season’s biggest games.“Senior class, we just said an emotional goodbye to them,” Meyer said after the Orange Bowl loss. “It’s not because they’re seniors, it’s because of what they’ve done. I tried to make that perfectly clear. Just because you stay some place for a couple years doesn’t mean you deserve that respect. It’s what you did, and how you did it.”The seniors on the offensive side of the ball turned in a record-setting season in their last year at OSU, setting school records for points (637), points per game (45.5), yards per game (512.0), passing touchdowns (38), first downs (361) and rushing yards (4,321).The Buckeyes had chances to win both postseason games late, but ultimately fell short. It is that unwillingness to give up that sets them apart, senior wide receiver Corey “Philly” Brown said after the loss to the Tigers.“(We have) great leadership, especially the senior class. It’s a tough football team. A team that will never give up,” Brown said.When Meyer’s reign began in 2012, a change in the culture came along with it, something Mewhort said was not an easy adjustment.“I know it looks like immediately the next season after going 6-7 we came back and go 12-0, but it was not immediate — at all,” Mewhort said. “It started at 5 a.m. in January of last year. Every day we came to work and we grinded hard.”Aside for Ryan Shazier — who declared for the NFL Draft Saturday — OSU will be leaning on juniors like quarterback Braxton Miller, tight end Jeff Heuerman, defensive lineman Michael Bennett and wide receivers Devin Smith and Evan Spencer in 2014 to follow in the footsteps of a class who Meyer thinks has a bright future.“It will be great. A student-athlete at Ohio State University, (will) get a great degree, and go on and build for the future,” Meyer said. “It’s going to sting for a while, probably a long while, because we just didn’t finish, and it was right there to finish.“This year’s senior class … When I looked around the room, every one of them could impact that play. And that’s the sign of a decent senior class.”No matter how it ended, Mewhort said being remembered for getting the program “back to where Ohio State should be” is the most important thing.“Talking about the last two games, obviously we would have liked to come out on top of those but I think our seniors did a good job of setting the template of how to come to work every day,” Mewhort said. “Do things the right way on and off the field. Hopefully we’ll be remembered for that.” read more


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first_imgReports in England have suggested that Pep Guardiola will renew his efforts to sign Isco from Real Madrid this summer with a reported £75m bid on offer, claims The SunCity are known to be keen admirers of Isco and were reported to have made their interest know to the Spanish international last summer, but Isco chose to remain at the Santiago Bernabeu for another season.The Sun have reported that City are now prepared to renew their efforts to sign the highly-rated midfielder, who could potentially be allowed to leave the squad in the summer as part of the rebuilding process being planned at Real.norwich city, manchester city, premier leagueReport: City are stunned by Norwich George Patchias – September 14, 2019 Manchester City was stunned by Norwich City in todays Premier League clash.Much has been made in recent days of the potential impact of Aymeric…The former Malaga player has made 24 starts for Real in an otherwise lacklustre title defence in La Liga with the club currently 15 points behind leaders Barcelona in third place.The English newspaper states that City are prepared to table a bid in the region of £75m for a player who gone to score 40 goals in 223 appearances for Real.last_img read more


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first_imgFormer Real Madrid manager Fabio Capello thinks Cristiano Ronaldo and Lionel Messi showed a lack of respect for skipping the FIFA Football Awards show.Both players made it to the FIFPro World XI, while Juventus striker Ronaldo made it to the final three for Player of the Year and was nominated for the Puskas award.However, neither man turned up for the ceremony in London, and rumours are rife that Ronaldo decided to boycott the show after hearing that Luka Modric would win the big prize.That news didn’t go down well with Italian gaffer Capello who criticised the attitude of the former winners.FC Barcelona, Valencia CFMatch Preview: Barcelona vs Valencia Boro Tanchev – September 14, 2019 Is derby time in La Liga, as Barcelona welcomes Valencia to the Camp Nou Stadium tonight at 21:00 (CET).“It’s a lack of respect that they didn’t come,” Capello told Mundo Deportivo.“When the Oscars happen, they [the nominees] are all there. It’s possible they’ve won too often, and they don’t like to lose.“But you have to be gracious when you lose, just like when you win.”last_img read more


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first_imgGianluigi Buffon feels that Cristiano Ronaldo’s summer arrival likely stopped more Juventus players from following him out of the clubThe veteran goalkeeper chose to end a 17-year stay with Juventus at the end of last season in favour of a free transfer to Paris Saint-GermainBut Buffon thinks he wouldn’t have been the only summer departure from Turin had Ronaldo not arrived from Real Madrid in a €112m deal.“For me, it was time to say ‘enough’,” Buffon told Tiki Taka on Sport Mediaset on Twitter.“Juve probably felt others could’ve left and that the only way to reawaken everyone was buying Cristiano.”Despite missing out on the chance of playing with the five-time Ballon d’Or winner, Buffon has no regrets on his decision to go to France.PSG, Neymar, Ligue 1PSG ultras sent a warning letter to Neymar Manuel R. Medina – September 14, 2019 Brazilian superstar Neymar might play today his first game of the season for Paris Saint-Germain and the team’s ultras have warned him.“I think, speaking in a friendly way with the president after such a long and stressful period because being a Juventus player and captain weighs on you a little, even if it’s an honour, the time had come for us to go our separate ways,” Buffon added.“I considered retiring or carrying on playing if an incredible offer from a top club came my way. If it had come from an exotic League, I wouldn’t have considered it.“The offer from PSG arrived in May, and it made me consider the option of playing for another year or two.“It was an unnatural choice but one I thought about a lot. We left each other on sweet terms, that’s what I wanted and I think everyone else did too.“I won seven Scudetti in a row and even if you’re stronger, you never take winning for granted. It involves so much nervous fatigue.”Buffon has made 10 appearances in all competitions for PSG this season.last_img read more


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first_img X 00:00 /01:26 – / 7There’s no perfect formula for staying sustainable as a small theater company. But in the case of Houston-based Obsidian Theater and Standing Room Only Productions, the idea is to become stronger as one. For Obsidian’s Executive Director Tom Stell, the extra help from SRO’s staff could increase productivity and opportunity. “Those people will be helping us on all the shows this next coming year, whether they be musicals or plays,” Stell says. “So we’ll just have a lot more bandwidth, artistically and businesswise.”Each company specializes in fringe theatre – which is usually less mainstream and more experimental. They’re both about six years old, but only Obsidian has been non-profit. SRO has operated as an LLC, but that changes with the merger. “By merging with [Obsidian], we’re going to be part of that non-profit,” explains SRO’s Artistic Director Rachel Landon. “And we’re going to enjoy the benefits of being a non-profit.” Some of those benefits include becoming eligible for other sources of funding, such as grant money. While the merger means Obsidian will lose revenue from renting the venue to SRO for their musicals, Stell is confident they can make up the loss. “I think we’re hoping to leverage those larger audiences we get from the musicals to support the plays,” he says.The groups will call themselves Obsidian Theater in association with SRO Productions to assist in the transition for the first season. After that, the group will become known as Obsidian Theater. To embed this piece of audio in your site, please use this code: Share Listen last_img read more