Jacks release football schedule

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first_imgTwo trips to the Lone Star State highlight the 2018 Humboldt State football schedule released on Thursday. The Green and Gold will play 10 games, including four at the Redwood Bowl.HSU faces a challenging schedule beginning with a road trip to Wichita Falls, Texas, to face Midwestern State on Sept. 1. The Mustangs reached the NCAA playoffs last season with a 10-1 record. The programs will meet for just the second time.Following a week off and a road game at Central Washington on Sept. 15, the …last_img


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first_imgWatching molecular machines at work in living cells should be as fascinating as watching a city through a magnifying glass.Observing biological nanotransporters (Science Daily). What if you could watch drawbridges working on the head of a pin? Something like that, but far smaller, works inside your cells. There’s a “nanoporter” that uses ATP to transport cargo in and out of cell membranes. This system is not as simple as A-B-C, even though it has that name.“ABC transporters are fascinating biological nanomachines,” says Lars Schäfer, head of the Molecular Simulation research group [at Ruhr-University Bochum]. These proteins couple the binding and chemical cleavage of ATP molecules, the chemical energy unit of the cell, with the transport of molecules through biological membranes….“Our results show how the binding of ATP molecules induces structural changes in the transporter that are ultimately required to carry substrate molecules through the membrane,” explains Hendrik Göddeke, co-author and doctoral researcher in Lars Schäfer’s group.Study reveals the inner workings of a molecular motor that packs and unpacks DNA (Phys.org). A chromosome remodeler named INO80 is performing onstage at the Ludwig Maximilian University of Munich: on the microscope stage, that is. Researchers at LMU watched the act of “astonishing precision” as it worked on its “heavy-duty reorganizational task” of wrapping DNA around chromatin.Chromatin remodelers have an essential role as they are molecular machines: they unpick and unpack segments of the DNA by sliding nucleosome spools back and forth, replacing individual histones, freeing up the DNA for transcription, and finally compacting it again, when the job is done. Since all of this happens in a highly dynamic fashion, chromatin remodelers enable cells to react rapidly to alterations in their environment – and this holds for brewer’s yeast as well as for human cells.The clouds of spaghetti that keep DNA data safe (Science Daily). Computer systems worry about data breaches, and so do cells. The cell nucleus is like a massive library read by numerous machines. They deliver information to the cytoplasm outside the nucleus, but only certain molecules can get in or out. This article describes some of the data protection systems provided by the Nuclear Pore Complexes (NPCs), some of the most complex machine systems in cells.Molecular machines (Illustra Media)Cells can avoid “data breaches” when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert Einstein College of Medicine have shown. Their study appears in the March 23 issue of the Journal of Biological Chemistry….To travel through NPCs, many molecules must be attached to proteins called transport factors (TFs), which act as shuttles that the NPC recognizes. But the NPC faces a challenge: It must accurately recognize and bind to TFs to let them through without admitting unwanted traffic, but it must let them through quickly — in a matter of milliseconds — in order for the cell to be able to do its duties. Proteins known to accurately bind to specific molecules, like antibodies, normally stay stuck to their targets for periods of up to months.“How on Earth do you have the kind of specificity that we see in protein-protein interactions like antibodies, and yet have the kind of speed that we see with water off a Teflon pan?” asked Michael Rout, professor at Rockefeller University who was one of the co-lead authors of the work.The spaghetti trick involves many intrinsically-disordered proteins in the NPC, looking somewhat like strands of spaghetti, making “many quick, transient contacts between transport factors” and nuclear proteins. How can we visualize this? “I can’t think of any analogy in normal life that does what this does,” Rout said. “You’ve got this blur of (amino acids) coming on and off (the transport factor) with extraordinary speed.” Maybe security engineers could learn something from this technique.Scientists map the portal to the cell’s nucleus (Science Daily). In this second article from Rockefeller University about the NPC, Rout did find one analogy:It reminds us of a suspension bridge, in which a combination of sturdy and flexible parts produce a stress-resilient structure, says Michael P. Rout, who led the work together with Brian T. Chait.The pore complex contains 552 component proteins, called nucleoporins, and scientists hadn’t previously known how they all fit together. It took a combination of approaches to assemble a comprehensive map of these pieces.Sadly, after comparing the NPC to lesser systems designed intelligently by humans, Rout ascribes it all to evolutionary chance. “Evolution has enclosed it with a double membrane, the nuclear envelope,” the article says, going on to visualize some unobserved miracles:The pore complex first emerged when single-celled organisms — the only living things at the time — acquired special compartments containing organ-like structures, including the nucleus, which houses the cell’s genetic code.Strings of electron-carrying proteins may hold the secret to ‘electric bacteria’ (Phys.org). This article suggests that some bacteria may have the ability to transfer electrons from the inside to the outside environment, using “micro machines” that turn on the power to extract energy from the environment. “Could a unique bacterium be nature’s microscopic power plant?” asks Moh El-Naggar, scientist at USC. Isn’t it nice to know that bacteria, “wired for survival” as among the smallest organisms on earth, are “highly evolved machines”?Microbiologists, can you please please turn off the obligatory Darwinspeak and just tell us the facts of what you are looking at? You’re beginning to sound like comedians. (Visited 422 times, 1 visits today)FacebookTwitterPinterestSave分享0last_img read more


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first_img14 July 2011 South African hospitality group Singita Game Reserves is now firmly at the top of the industry after walking off with the honours in the 2011 US Travel + Leisure World’s Best Awards readers’ survey. Singita’s safari hotels and lodges were rated against top competition from around the world. Its Grumeti Reserves, situated close to the Serengeti National Park in Tanzania, came in at number one on Travel + Leisure World’s list of 100 top hotels. Also, Singita’s flagship Sabi Sand, located within the greater boundaries of the world-famous Kruger National Park, was ranked at number two. Sabi Sand features Singita’s original lodges, Singita Ebony and Singita Boulders, as well as the Singita Castleton, an exclusive-use facility. As if this wasn’t enough, the Singita Kruger National Park, overlooking the N’wanetsi River in the park’s northern region, rounded off the honours for the group by taking the 39th spot on the list, and was also named the best Hotel Spa in Africa and the Middle East. The Travel + Leisure World’s Best Awards are given to top hotels, destinations, airlines, cruises, outfitters and transportation companies in the world. The winners are chosen by readers in a survey where they are rated on a scale of one to five, with five being excellent. The winners of this year’s survey, the 16th edition, were announced on 7 July on US television channel NBC’s Today Show. They were due to receive their awards at a ceremony in Los Angeles on 14 July.Practising modern conservation Singita Reserves’ chief marketing officer, Lindy Rousseau, said: “Singita today manages and is responsible for 570 000 acres in Africa. We operate ten lodges in four destinations in three countries.” The group practises so-called modern conservation, said Rossouw. She described the concept as “a finely tuned relationship between wildlife, local communities and tourism”. Singita is committed to tourism that delivers a high value but leaves a low impact on the environment, meaning that habitats are sensitively managed. As a result, animal populations are thriving in Singita areas. As an example, said Roussouw, a mere eight years ago hardly an animal was seen in Grumeti, but today it boasts the most prolific game populations in East Africa. “We spend more on wildlife projects and community development than anyone else,” said Rousseau. She expressed her gratitude at the honour of being voted a world leader by some of the most discerning travellers to be found anywhere.African splendour The results of the survey attest to the splendour of Africa’s natural scenery, the attraction of its great hospitability, and the enchantment it leaves on those who have travelled and stayed there. Singita describes the impact of its destinations on guests as “nothing short of life changing”. The group’s luxury lodges can be found in South Africa, Tanzania and Zimbabwe. In South Africa, the Singita Ebony and Singita Boulders lie within the world’s best leopard viewing area, while the Singita Castleton, a private six-roomed villa, is situated close to one of the most frequented waterholes in the Kruger National Park. Guests can spot the Big Five – lion; leopard; rhino; elephant and buffalo – at these locations. In Tanzania, home of the world’s best hotel; millions of wildebeest can be seen during the migration season as the hotel is located on a prime viewing site along the animals’ annual route. In Zimbabwe, Malilangwe Wildlife Reserve is a haven for endangered species like the black rhino. The reserve has a vast collection of baobab trees and offers breathtaking views of the Malilangwe Dam. Rousseau said: “When it comes to hotels, the new world order is very different from just five years ago. Today it is about authenticity, integrity and being real. I think this is why more and more guests identify with what we are doing.” First published by MediaClubSouthAfrica.com – get free high-resolution photos and professional feature articles from Brand South Africa’s media service.last_img read more


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first_img10 September 2013Retailer Massmart is to use the international reach of US parent company Walmart to increase export opportunities for emerging South African wine makers under its Developing Wine Brand programme, the company said on Friday.This follows the successful entry of the popular Seven Sisters wines and Zulu King Goodwill Zwelithini’s royal brand Bayede! Wines into the US and China respectively in the last year.Seven Sisters wines are now on the shelves of 300 Walmart stores in the US, after launching in 54 stores in August 2012, while Bayede! Wines recently shipped around 35 000 bottles to China, also under a contract with Walmart.Massmart said on Friday that it would be looking for superior quality wines from its Developing Wine Brand programme to recommend to Walmart.According to the company, the 19 participating brands have sold almost 17 000 bottles locally since the launch of the programme in March 2012. All 19 brands are now available in Makro stores as well as selected Game stores countrywide.“We have learnt so much during the first year and have been able to tweak the offering,” Massmart’s supplier development manager, Moshisi Lehlongwane, said in a statement.To begin with, participants received consulting advice on issues such as customer analysis, packaging and pricing. However, it soon became clear that getting the wines from farm to store was the biggest challenge, and Massmart now provides logistical support, with backing from Cool Wines.“We aim to achieve this by providing a route to market for our participating wines, mainly through Makro and other liquor chains in Massmart,” said Carolyn Barton, Makro’s national wine buyer. “We also assist with distribution, in-store marketing, promotional support and training.”SAinfo reporterlast_img read more


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first_img Posted on March 10, 2019Author Nathalie DuboisCategories HairpiecesTags Unknown SummaryReviewer Nathalie DuboisReview Date2019-03-10 12:40:04Reviewed Item Love Hair Extensions Curly Crocodile Clip Synthetic Hair Ponytail Colour 1 Jet Black 12 -InchRating 2.0 / 5  stars, based on  14  reviews I would 100% recommend this everyones thought it was real, and asked me whos done my hair ect, and it saves alot of time taking ages to put hair extensions in. Looks a lot nicer that it does in the picture. Hair feels very soft and natural. Nice length too and very easy to put in. Excellent colour and quality. Very good service all round. Colour is good and texture is also good. Overall i wish there had been a lighter shade available. How great not to bother washing hair every five mins on hol just tie it up and clip this hair piece on and you are good to go . Comfortable to wear and the colour is beautiful. Item worked a treat, i wore it for a races day out and it stayed in place for 12+ hours, and my natural hair is very fine so it didn’t have much to cling on to. This clip in ponytail looks good i got my hair colour to match the hair on the ponytail perfectly the only thing is that you can tell its a clip in one as no one can see a bobble in your hair where the clip is but other wise it looks greatlove hair extensions curly drawstring synthetic hair ponytail colour 8 mousey brown 12 -inch. My daughters told me i looked like a princess the first time i wore it. So easy to put inabsolutely gorgeous. Compliments everytime i wear itdefinately recommend it. Wonderful product and good price. Easy tidy up FAST DELIVERY. GREAT PRODUCT. Love Hair Extensions Curly Crocodile Clip Synthetic Hair Ponytail Colour 1 Jet Black 12 -InchAvailable in 7 styles and a drawstring and crocodile clip attachmentAffordable, effective, safe and funTransform your look in minutes!Re-use time and time againMade from premium synthetic fibre Five Starslast_img read more


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first_imgShare Facebook Twitter Google + LinkedIn Pinterest A government program intended to support farmers and ranchers affected by trade disputes disproportionately benefitted large-scale and Southeastern operations, according to a minority staff report published by the U.S. Senate Committee on Agriculture, Nutrition, and Forestry.The U.S. Department of Agriculture (USDA) program, known as the Market Facilitation Program, compensated most commodity grain producers based on a single county rate per planted acre. National Farmers Union (NFU) initially expressed concern that the payment disparities among counties would put some farmers at a financial disadvantage, a fact that has been confirmed by today’s report. Although farmers in the North, Midwest, and West have experienced the greatest harm from trade disputes, 95% of counties receiving the highest payment rates are based in the Southeast. Even in adjacent counties, payment rates sometimes vary by two to three times.“Farmers in every county have been affected by withering export markets,” said Roger Johnson, NFU president. “Yet these county payment rates arbitrarily have helped farmers in some counties much more than others. If you’re unlucky enough to live in a county with a low payment rate, you may have received just a third of the assistance that your next-door neighbor got — for no apparent reason at all.”NFU was similarly worried that the vast majority of trade assistance would flow to the largest operations rather than more vulnerable small- and medium-sized operations; by some estimates, more than half of the first tranche of payments went to just one-tenth of the recipients. Since then, USDA doubled the payment limit for row crops from $125,000 to $250,000 and loosened income restrictions, paving the way for millionaires to claim an even larger share of assistance.With the number of mid-sized farms already rapidly declining, Johnson was perturbed that MFP would accelerate the alarming trend of farm-level consolidation.“During times of financial difficulty like these, bigger farms with more equity have a cushion to protect them from low prices and bad weather. But smaller operations might not be able to withstand more than a few hard years in a row,” Johnson said. “A successful food system is a diverse food system, with farms of all types and sizes. Unfortunately, USDA’s preferential treatment of larger operations will likely contribute to the ongoing homogenization of American agriculture.”Flaws aside, these programs are just a temporary solution to the very long-term damage inflicted on the United States’ trade relationships.“Trade assistance payments are not an economically sustainable way for farmers to make ends meet,” Johnson said. “Though assistance payments have proved critical to the immediate financial stability of family farmers and ranchers, their continued success depends on stable markets and fair prices. Farmers work hard to feed, fuel, and clothe America — and they should be able to make a living doing just that. We urge President Trump to work with Congress to establish policies that ensure that farmers no longer have to depend on outside help just to stay in business.”last_img read more


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first_imgA five-year-old girl, daughter of a migrant labourer, was brutally raped by unidentified men in Dasuya town in Hoshiarpur district, police said on Tuesday.The girl was admitted to the Civil Hospital, Dasuya from where she was referred to PGIMER, Chandigarh, in a critical condition after the incident on Monday night, they said.Police said the girl went missing from her house last night at about 10:30 p.m. when there was a power shutdown in the area. The family members lodged a missing report with the Dasuya police station late on Monday night. On Tuesday, a passer-by noticed the girl lying in an unconscious state near a railway track. Some blood stained clothes were also found there.The father of the girl is a migrant labourer, police said. Dr. Rajesh Bagga, Senior Medical Officer at Dasuya Civil Hospital, confirmed gang rape and said the victim suffered external as well as internal wounds. A case was registered at the Dasuya police station under relevant provisions of the POCSO Act and the IPC, police said.last_img read more


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first_img(Vicki Monague filed complaint over RCMP’s handling of her criminal allegation of domestic violence against Onion Lake Cree Nation Chief Wallace Fox. Photo supplied by Monague.)Jorge Barrera APTN National NewsThe RCMP is probing complaints filed against officers from the Onion Lake Cree Nation detachment over their handling of a domestic violence allegation against Chief Wallace Fox, APTN National News has learned.Fox, the long-time chief of the Saskatchewan First Nation, was charged Monday with two counts of assault, one count of possession of a dangerous weapon and one count of uttering threats to damage property stemming from a domestic incident at his Onion Lake residence. He is scheduled to appear in provincial court on Dec. 16.Toronto-based investigators with the RCMP Professional Standards Unit are also currently probing how the Onion Lake RCMP detachment handled the allegations against Fox.The probe was triggered after the alleged victim filed a complaint with the Civilian Review and Complaints Commission for the RCMP.The charges were laid nearly six months after Vicki Monague, who is from Beausoleil First Nation in Ontario, filed her criminal allegation against Fox with the RCMP detachment at Onion Lake.A spokesperson for Fox said he would not be commenting on the charges because the matter is now before the courts.Monague said she was informed by the Saskatchewan Crown last week that he had recommended charges against Fox. Still, she said she was “shocked” when Fox was finally charged.“This has been going on now for nearly six months. We didn’t know how to feel about it. I think we are in kind of shock mode right now and we are starting to figure out what this actually means,” said Monague. “I think for me and my kids especially the hardest part has been the anxiety attacks and watching somebody that we know personally behind closed doors on the news, in media articles on social media being an advocate for murdered and missing Indigenous women.”Monague said she filed her complaints against the detachment’s officers in Onion Lake because she felt they didn’t take her domestic violence allegations seriously. Monague said she was initially told by one officer at the Onion Lake detachment that she had to appear in person if she wanted to press any charges against Fox.“I was fearful of my husband and left Onion Lake Cree Nation to return home,” said Monague, in her letter of complaint dated July 3. “I was also fearful that had I pressed charges, Wallace Fox, being the chief, would have interfered with those charges proceeding through political means.”Staff Sgt. Paul Dickinson and a sergeant from the RCMP’s Professional Standards Unit interviewed Monague on Oct. 1 about her complaint against four RCMP officers, including three from the Onion Lake detachment and the staff-sergeant who originally handled her complaint against the detachment. The interview was held at the OPP detachment in Midland, Ont.The Onion Lake detachment commander has already received “verbal operational guidance in the area of compassion when dealing with victims of crime” as a result of the complaints, according to a copy of a complaint intake document obtained by APTN.Monague said she had been living with Fox since October 2014 and had been involved in a relationship with him since July of the same year. The alleged incident occurred at Fox’s residence on May 13, said Monague.Monague said she filed her domestic violence allegations on May 18 after she arrived in Beausoleil First Nation, in Ontario, following a four-day drive from Saskatchewan.Monague said she and her children, aged 11, 12 and 14, issued sworn statements before a commissioner of oaths on June 8 alleging domestic violence. Monague said she gave her statement at the Midland police detachment and her children issued their statements at the Anishinabek police detachment.Monague said the statements were sent by Purolator Courier but were not picked up by Onion Lake RCMP until June 30, according to her letter of complaint.“I have seen corruption within the Onion Lake RCMP and they have failed to protect me and my children,” she said. “But my main concern is, what about other women. How many other women could there be that came forward and the police refused to investigate. How many other women have they done this to?”jbarrera@aptn.ca@JorgeBarreralast_img read more